已知的 白藜芦醇 功能

白藜芦醇 这种全身功效是因为全身细胞的基因相同： 都有SIRT1基因。 通过血液循环到达全身各细胞，与基因SIRT1结合产生抗衰老蛋白, 达到保健的目的，是真正的基因营养品。 似乎没有亚健康状态， 没有形成疾病， 让动物多活30%， 无疾而终! 白藜芦醇发挥了生命的潜力!

白藜芦醇的研究几乎引起了所有生命科学家的兴趣! 白藜芦醇益处有许多，在现代科学研究基础上已知的白藜芦醇功能有：

1. 1. 延长寿命 (12，13)
   2. 增强免疫系统 (25)
   3. 预防心血管疾病 (15),(16)
   4. 防治糖尿病 (13, 34)
   5. 维护肝功能 (13, 34)，
   6. 男性天能威而刚, 改善前例腺问题(21)
   7. 舒缓更年期障碍 (12，22)
   8. 提高生殖能力(12，22, 35)
   9. 减肥瘦身(13)
   10. 防止细胞癌变， 抑制肿瘤 (13，23, 24)
   11. 抗过敏， 气喘 (27， 28)
   12. 解毒排毒，保护肾脏(28)
   13. 防治忧郁症, 镇定安眠(17, 18, 19, 20)
   14. 预防骨质疏松症 (13， 29， 31)
   15. 防治皮肤衰老, 刺激胶原蛋白的产生, (32)
   16. 防治流感病毒和其它病毒(33)
   17. 减轻关节炎疼痛, 有效消除颈椎腰椎疼痛 (26, 36， 37)
   18. 抑制眼睛内毛细血管破裂，预防失明(38)
   19. 抑制听力下降(39)

您遇到过这些疾病的病人吗? 了解病人的痛苦吗? 您希望您的家人，朋友，同事远离疾病的痛苦吗? 被疾病夺去亲人的悲伤，又有谁没有经历过? 流感造成的痛苦， 您还记得吗? 别的疾病比流感严重十倍， 百倍。

所列功效后在括号中的文献均来自科学杂志。 白藜芦醇能防乳腺癌和缩小乳腺肿瘤， 是因为白藜芦醇能减少乳腺肿瘤细胞生长所需的蛋白质-低氧诱导因子， 从而引导乳腺癌细胞死亡(39A)。 其实， 癌症生成的原理是一样的， 所以，白藜芦醇对胃癌， 前列腺癌， 血癌， 淋巴癌，甲状腺癌等等均有疗效(见证录)。 我们身体里的癌细胞是细胞衰老造成的， 时刻都在。一旦不能清除， 便形成癌症。 现在已经十分明了： 我们大家为什么需要用白藜芦醇!

参考文献:

(1). Hills, B. The island of the Ancients. TheSecrets of Sardina’s Centenarians. Murdoch Books, 2008

(2). We will be able to live to 1,000’。 By Dr Aubrey de Grey University of Cambridge。 BBC on line news 3 December, 2004

(2A). Atul Gawande, Being Mortal. Published October 7th 2014 by Metropolitan Books

(2B). Jared Mason Diamond. The Rise and Fall of the Third Chimpanzee: Evolution and Human Life. Hutchinson Radius, 2004

(3). “Live to 150, Can you do it?”, ABC Special TV program, August 24, 2012

(4). National Geographic, May 2013

(5) Klatz, R. and Goldman, R. The New Anti-Aging Revolution. Basic Health Publications, Inc. 2003

(6). The Healing Power of Vitamins and Minerals & Herbs. Readers Digest. 2000

(7). 邝安坤. 老年医学在中国。 湖南科学技术出版社 CHINA 1989.

(8). Can Meditation really slow aging? Australia Readers digest. February 2015

(9). Strand, R.， 别让不懂营养学的医生害了你 What Your Doctor Doesn’t Know about Nutritional Medicine May Killing You. 中国青年出版社 2009

(10).Stableford, B. Future Man. Crown Publishers, Inc, USA 1984

(10A). Sears,B. (2000). The Age-Free Zone. ReganBooks, A Imprint of HarperCollinsPublishers

(10B). Grimm Brothers; Margarate Hunt (Translator) (1944). Death’s Messengers (Die Boten des Todes) The Complete Grimm’s Fairy Tales. New York: Pantheon Books

(11).武振娟， 李莉。 葛洪的养生之道研究。 兰台世界， 2012， 12

(12).Valenzano, D., Terzibasi, E., Genade, T., Cattaneo, A., Domenici, L. And Cellerino, A. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Current Biology 16, 2960300, Febuary 7, 2006.

(13).Baur, J. A., Pearson, K, J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., Pistell, P. J., Poosala, S., Becker, K.G., Boss, O., Gwinn, D., Wang, M., Ramaswamy, S., Fishbein, K. W., Spencer, R. G., Lakatta, E. G., Couteur, D. L., Shaw, R. J., Navas, P., Puigserver, P., Ingram, D, K., de Cabo, R., & Sinclair, D. A. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342 (16 November 2006)

(14).60 minutes. CBS Nov 17, 1991

(15).Kaga, S., Zhan L., Matsumoto, MMaulik N., Resveratrol enhance neovascularisationin the infracted rat myocardium through the induction of thioredoxin-1,heme oxygenase-1 and vascular endothelial growth factor. J. Molecular and Cellular Cardiology. Vol. 39, Issue 5. Nov. 2005

(16).Paolo Gresele， Pasquale Pignatelli， Giuseppe Guglielmini， Roberto Carnevale， Anna Maria Mezzasoma， Andrea Ghiselli， Stefania Momi, and Francesco Violi。 Resveratrol, at Concentrations Attainable with Moderate Wine Consumption, Stimulates Human Platelet Nitric Oxide Production。 J. Nutr. September 2008 vol. 138 no. 9 1602-1608

(17).McCrone, J. Going Inside. Published by Faber and Faber, 1999

(18).Capiralla H, Vingtdeux V, Zhao H, Sankowski R, Al-Abed Y, Davies P, Marambaud P. Resveratrol mitigates lipopolysaccharide- and A□mediated microglial inflammation by inhibiting the TLR4/NF-kB/STAT signaling cascade. J Neurochem. 2011 November

(19).X. J. Meng,* F. Wang, and C. K. Li。 Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats。 Indian J Pharm Sci. 2014 Mar-Apr; 76(2): 125ǔ131

(20).Hurley LL1, Akinfiresoye L1, Kalejaiye O1, Tizabi Y。Antidepressant effects of resveratrol in an animal model of depression. Behav Brain Res. 2014 Jul 15;268:1-7. doi: 10.1016/j.bbr.2014.03.052. Epub 2014 Apr 6.

(21).Ourique GM1, Finamor IA, Saccol EM, Riffel AP, Pes TS, Gutierrez K, Goncalves PB, Baldisserotto B, Pavanato MA, Barreto KP. Resveratrol improves sperm motility, prevents lipid peroxidation and enhances antioxidant defencesin the testes of hyperthyroid rats。 Reproductive Toxicology。 Volume 37,June 2013, Pages 31-39

(22).Juan ME1, Gonzaez-Pons E, Munuera T, Ballester J, Rodriuez-Gil JE, PlanasJM. trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in healthy rats。 J Nutr. 2005 Apr;135(4):757-60

(23).Minutolo, F., Sala, G., Bagnacani, A., Bertini, S., Carboni, S., Placanica, G, Prota, G, Rapposelli, S, Sacchi, N. And Ghidoni, R. Synthesis of a resveratrol analogue with high ceramide-madiated proappoptotic activity on human breast cancer cells. J. Medicinal Chemistry 48: 6783-86, 2005.

(24).Zhang, Q., Tang, X., Lu, Q., Zhang, Z., Brown, J., and Le, A. Reseveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamouse cell carcinoma and hepatoma cells. Mol Cancer Ther. Oct;4(10):1465-74, 2005.

(25).Wong YT, Gruber J, Jenner AM, Tay FE, Ruan R. Chronic resveratrol intake reverses pro-inflammatory cytokine profile and oxidative DNA damage in ageing hybrid mice. Age (Dordr). 2011 Sep;33(3):229-46.

(26).Gao Xuzhu， Mousa Komai-Koma, Bernard P Leung， Hwee Siew Howe, Charles McSharry, Iain B McInnes, Damo Xu。 Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function。 Ann Rheum Dis 2012;71:129-135

(27).Jing Chen,Sang-Myeong Lee, Deyu Fang, and Ulus Atasoy。The therapeutic role of resveratrol in allergic lung inflammation。 The Journal of Immunology, 2010, 184, 97.2

(28).Meltem Kolgazi, , Gsel Sener, , Sule Gtinel, , Nursal Gedik, M.D.□ Inci Alican, M.D. Resveratrol Reduces Renal and Lung Injury Caused by Sepsis in Rats。J. Surgical research. August 2006Volume 134, Issue 2, Pages 315-321

(29).Jian Zhang, Oxana P. Lazarenko, Michael L. Blackburn, Thomas M. Badger, Martin J. J. Ronis, Jin-Ran Chen。 Blueberry consumption prevents loss of collagen in bone matrix and inhibits senescence pathways in osteoblastic cells。AGE。 June 2013, Volume 35, Issue 3, pp 807-820

(30).Uysal T, Gorgulu S, Yagci A, Karslioglu Y, Gunhan O, Sagdic D: Effect of resveratrol on bone formation in the expanded inter-premaxillary suture:early bone changes Orthod Craniofac Res 2011;14:80-87

(31).Stephanie M. Durbin, Janna R. Jackson, Michael J. Ryan, Joseph C. Gigliotti,Stephan E. Alway, Janet C. Tou。 Resveratrol supplementation preserves long bone mass, microstructure, and strength in hindlimb-suspended old male rats。 Journal of Bone and Mineral Metabolism。 May 2013

(32).Mary Ndiaye,a Carol Philippe,a Hasan Mukhtar,a,b and Nihal Ahmada,b,*Author information _ Copyright and License information _he Grape Antioxidant Resveratrol for Skin Disorders: Promise, Prospects, and Challenges。 Arch Biochem Biophys. 2011 Apr 15; 508(2): 164ǔ170.Published online 2011 Jan 4. doi: 10.1016/j.abb.2010.12.030

(33).Palamara AT1, Nencioni L, Aquilano K, De Chiara G, Hernandez L, Cozzolino F, Ciriolo MR, Garaci E。 Inhibition of influenza A virus replication by resveratrol.J Infect Dis. 2005 May 15;191(10):1719-29

(34).Jennifer L. Fiori1, Yu-Kyong Shin1,2, Wook Kim1,3, Susan M. Krzysik-Walker1, Isabel Gonz lez-Mariscal1, Olga D. Carlson1, Mitesh Sanghvi1, Ruin Moaddel1, Kathleen Farhang1, Shekhar K. Gadkaree1, Maire E. Doyle4, Kevin J. Pearson5,6, Julie A. Mattison5, Rafael de Cabo5 and Josephine M. Egan1_Resveratrol Prevents □Cell Dedifferentiation in Nonhuman Primates Given a High-Fat/High-Sugar Diet。Diabetes October 2013 vol. 62 no. 10 3500-3513

(35).Balestrieri, M., Schiano, C., Felice, F. Casamassimi, A., Balestrieri, A.,Milone, L., Servillo, L. Ad Napoli, C. Effect of lo doses of red wine and pure resveratrol on the circulating endothelial progenitor cells. J.Biochem.143, 179-0186,2008.

(36).Young-Joon Kwon。 Resveratrol Has Anabolic Effects on Disc Degeneration in a Rabbit Model。 J Korean Med Sci. 2013 Jun; 28(6): 939-945.

(37).Wuertz K1, Quero L, Sekiguchi M, Klawitter M, Nerlich A, Konno S, Kikuchi S, Boos N. The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus-mediated pain in vitro and in vivo.Spine (Phila Pa 1976). 2011 Oct 1;36(21):E1373-84.

(38).Khan AA1, Dace DS, Ryazanov AG, Kelly J, Apte RS. Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway. Am J Pathol. 2010 Jul;177(1):481-92. doi: 10.2353/ajpath.2010.090836. Epub 2010 May 14.

(39).M. D. Seidman, W. Tang, V. U. Bai, N. Ahmad, H. Jiang, J. Media, N. Patel,C. J. Rubin, R. T. Standring. Resveratrol Decreases Noise-Induced Cyclooxygenase-2 Expression in the Rat Cochlea. Otolaryngology — Head and Neck Surgery,2013

(39A)Garvin S., Ollinger K and Dabrosin C. Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo. Cancer letters, Vol. 231, Issue No. 1 113-122 (2006).

(40).Fremont, Lucie. “Biological Effects of Resveratrol”. Life Sciences. Elservier, France. Retrieved 6 June 2014.

(41).Filippo Minutolo, Giusy Sala, Annalisa Bagnacani, Simone Bertini, Isabella Carboni, Giorgio Placanica, Giovanni Prota, Simona Rapposelli, Nicoletta Sacchi, Marco Macchia, and Riccardo Ghidoni。 Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells。 Journal Medicinal Chemistry 48, 6783-6786, 2005. pp 6783ǔ6786 Publication Date (Web): October 04, 2005 (Letter)DOI: 10.1021/jm050528k

(42).Liu Y, Ma W, Zhang P, He S, Huang D; Ma; Zhang; He; Huang (March 2014). “Effect of resveratrol on blood pressure: A meta-analysis of randomized controlled trials”. Clinical Nutrition 34 (1): 27ǔ34. doi:10.1016/j.clnu.2014.03.009. PMID 24731650.

Nagnun, D., Canadian Studies in Population. 1986, 13(1):83-102

(43).Timmers S,áKonings E,áBilet L,áHoutkooper RH,ávan de Weijer T,áGoossens GH,áHoeks J,ávan der Krieken S,áRyu D,áKersten S,áMoonen-Kornips E,áHesselink MK,áKunz I,áSchrauwen-Hinderling VB,áBlaak EE,áAuwerx J,áSchrauwen P. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 2011 Nov 2;14(5):612-22. doi: 10.1016/j.cmet.2011.10.002.

(44).Garvin S1, Ollinger K, Dabrosin C.， Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo. Cancer Lett. 2006 Jan 8;231(1):113-22

(45).Sangeeta Shrotriya, Rajesh Agarwal, Robert A. Sclafani. A Perspective on Chemoprevention by Resveratrol in Head and Neck Squamous Cell Carcinoma. Advances in Experimental Medicine and Biology, December 2014 DOI: 10.1007/978-3-319-09614-8_19

(46).Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis, Jr. and U. Kristina Walle。 HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS。 DRUG METABOLISM AND DISPOSITION， 32:1377-1382, 2004

(47).A Q&A Audience With Bill Gates， ABC， Australia, May 28, 2013

(48).Xu Y., Live healthier, Live longer and Liver forever。 (2006).

(49).Angela Epstein。 Old before your time: When your body really starts going downhill. Read more:ttp://www.dailymail.co.uk/health/article-1035037/Old-time-When-body-really-starts-going-downhill.html#ixzz3TqhXrvNE

(50).Kirsty L. Spalding, Ratan D. Bhardwaj, Bruce A. Buchholz, Henrik Druid, and Jonas Frisén. Retrospective Birth Dating of Cells in Humans. Cell, Vol 122, 133-143, 15 July 2005.

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